Innovative Drug R&D Solutions

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Sanyou Bio innovative mRNA to mAb service provides one-stop solution from target sequences to monoclonal antibody production in only 12 weeks, also including customized QA services for mRNA and LNP packaging (see the detailed procedures below). Contact with our experts for a customized service plan.

Note: additional time required for customized QC service plus 3-7 days of rotational periods.

Developmental History of Sanyou Bio mRNA mAb Platform

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mRNA-based technology has emerged as a cornerstone of molecular medicine, heralding a new era in therapeutic innovation. The Sanyou Bio mRNA mAb platform integrates the strengths of mRNA technology (Table 1) with our state-of-the-art antibody design, discovery, and production systems (Fig 1), overcoming the challenges of antigen production and antibody generation for complex and difficult targets.

Note: additional time required for customized QC service plus 3-7 days of rotational periods.

Comparisons of mRNA immunization over others

Cost for raw material preparation	High	Mid-low	Mid-low	Low
Time for raw material preparation	Slow	Mid	Mid	Fast
Complex targets（i.e. GPCR，ICR）	√	×	√	√
Immunization dose	High	Mid	Mid	Low
Immunization period	10 week（biweekly）	10 weeks（biweekly）	10 weeks（biweekly）	6 week（biweekly）
Adjuvant	Optional	Freunds Adjuvant	Freunds Adjuvant	Optional
Efficacy	High	Mid	Mid	Mid-high
Non-specific binding	High	Mid-low	Mid-low	Low
Storage conditions	-20°C，long time	-20°C，long time	-20°C，long time	-80°C，short time

Comparisons of mRNA immunization over others

Offers New Solutions to
Antibody Discovery
Combining with Current
Immunization Pathways

Addresses Challenges
in Complex
Target Antigen
Preparation

Overcomes
Non-Specific
Issues Caused by
Cellular Immunity

Significantly Shortens
Antibody Discovery
Cycle and
Reduces Costs

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